Download option alpha signals7/10/2023 ![]() ![]() RA reduces these miRNAs and increases SIRPα expression in SIRPα-negative promyelocytic cells. The SIRPα gene is a commonly targeted by miR-17, miR-20a, and miR-106a. Signal-regulatory protein α (SIRPα) is essential for modulating leukocyte inflammatory responses. Yu-Jui Yvonne Wan, in Methods in Enzymology, 2020 3 miRNAs that are implicated in RA-regulated inflammatory signaling and immunity
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